Papel del tejido conectivo en la morfología y función de la mucosa intestinal: su importancia en la patogenia de la enfermedad celíaca / Role of the connective tissue in the morphology and function of intestinal mucosa: its participation in the pathogenesis of celiac disease
Rev. méd. Chile
;
129(11): 1333-1342, nov. 2001. ilus, tab
Article
in Spanish
| LILACS
| ID: lil-302643
RESUMO
The differentiation, architecture and function of the mucosa of the digestive tract is the result of close interactions between the epithelial cells and their underlying connective tissue. This interaction not only plays a role in the normal morphological organization of the intestinal mucosa but also in the organization and maturation of the enterocytes, the development of some of their enzymatic activities, the transport of nutriens and the restitution of the epithelium following denudation of the surface of villi due to loss of enterocytes. It is thought that disturbances of the cells of the connective tissue, especially of the myofibroblasts as well as of some of the above mentioned mechanisms, participate in the pathogenesis of some gastrointestinal diseases, celiac disease among them. This review summarizes some of the knowledge in this area
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Celiac Disease
/
Connective Tissue
/
Intestinal Mucosa
Type of study:
Etiology study
Limits:
Humans
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2001
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Universidad de Chile/CL
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