Efeito do choque hipovolêmico na anastomose do intestino delgado de ratos / Effect of hypovolemic shock in anastomose of small intestine of rats
Arq. gastroenterol
;
38(2): 116-124, abr.-jun. 2001. tab, graf
Article
in Portuguese
| LILACS
| ID: lil-305367
RESUMO
OBJECTIVE:
Study the effect of hypovolemic shock on small intestinal anastomose in adult rats.METHOD:
Ninety male rats were randomly divided into five groups standard, hypovolemic shock, anastomose alone, hypovolemic shock + anastomose and hypovolemic shock + anastomose + blood reinfusion. Hypovolemic shock was achieved by bleeding 30% of the blood volume of the animal. A single layer extramucosal intestinal anastomose was performed. Following intestinal anastomose, the blood volume was restored in group shock, anastomose and blood reinfusion, using heparinized autologous. RESULTS ANDCONCLUSION:
In the experimental model used, hypovolemic shock provoked histological lesions to the mucosa and increased colagen fiber deposition into the submucosa in the region of intestinal anastomose which were progressive with post-operative period. In addition, when the hypovolemic shock group were pressure tested there was a tendency towards a weakening of the intestinal wall at day 7 which became more evident at day 21 as compared to the control groups.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Shock
/
Intestine, Small
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Limits:
Animals
Language:
Portuguese
Journal:
Arq. gastroenterol
Journal subject:
Gastroenterology
Year:
2001
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal de São Paulo/BR
/
Universidade do Estado do Pará/BR
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