Stereotactic fibrinolysis of spontaneous intracerebral hematoma using infusion of recombinant tissue plasminogen activator
Arq. neuropsiquiatr
;
60(2B): 362-366, June 2002. ilus, tab
Article
in English
| LILACS
| ID: lil-310851
ABSTRACT
PURPOSE: The authors present a prospective study on 10 patients with stereotactic infusion of tissue plasminogen activator (rtPA) intraparenchimal hemorrhage. METHODS: Between 1999 and 2000, 10 patients with deep seated hematomas in the basal ganglia were selected for stereotactic infusion of rtPA and spontaneous clot drainage. RESULTS: All cases had about 80 percent reduction of the hematoma volume in the CT scan at the third day. The intracranial pressure was normalized by the third day too. There were no local or systemic complications with the use of this trombolitic. The results were shown by the Glasgow Outcome Scale with six patients in V, three in IV and one in III after 3 months. CONCLUSION: Early treatment and drainage with minimally invasive neurosurgery , can make these patients with deep-seated hematomas recover the consciousness and they can be rehabilitated earlier avoiding secondary complications
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Recombinant Proteins
/
Stereotaxic Techniques
/
Tissue Plasminogen Activator
/
Basal Ganglia Hemorrhage
/
Intracranial Hemorrhage, Hypertensive
/
Fibrinolytic Agents
/
Hematoma
Type of study:
Observational study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Arq. neuropsiquiatr
Journal subject:
Neurology
/
Psychiatry
Year:
2002
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Estácio de Sá/BR
/
Universidade Federal de SãoáPaulo/BR
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