Prevelência da síndrome hepatopulmonar em candidatos a transplante hepático / Hepatopulmonary syndrome in liver transplantation candidates
Arq. gastroenterol
;
39(1): 11-16, jan.-mar. 2002. tab
Article
in Portuguese
| LILACS
| ID: lil-316273
ABSTRACT
Hepatopulmonary syndrome is an important clinical problem associated with chronic liver disease. Liver transplantation can result in complete resolution of the arterial hypoxemia associated with this syndrome, even in its most severe presentation. AIM:
To determine the prevalence of hepatopulmonary syndrome in adult liver transplant candidates. PATIENTS ANDMETHODS:
Fifty-four consecutives adult patients (> or = 18 years) with severe liver disease waiting for liver transplant were screened for arterial hypoxemia (PaO2 < 70 mm Hg) while they were seated, at rest, and breathing room air. Patients with arterial hypoxemia underwent contrast-enhanced two-dimensional echocardiography and pulmonary function testing. Hypoxemia (PaO2 < 70 mm Hg) was present in 7 of 54 patients (12.9%), although only 1 of them complained of dyspnea. The Child's classification of the patients were A = 1, B = 4, and C = 1. All seven hypoxemic patients had positive contrast-enhanced two-dimensional echocardiography, consistent with hepatopulmonary syndrome.CONCLUSION:
The prevalence of hepatopulmonary syndrome in adult liver transplant candidates is elevated. The screening for hepatopulmonary syndrome should be part of the routine evaluation of liver transplant candidates even in the absence of pulmonary symptoms
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Liver Transplantation
/
Hepatopulmonary Syndrome
Type of study:
Etiology study
/
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
Portuguese
Journal:
Arq. gastroenterol
Journal subject:
Gastroenterology
Year:
2002
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal do Paraná/BR
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