Transfer of toxin genes to alternate bacterial hosts for mosquito control
Mem. Inst. Oswaldo Cruz
;
90(1): 97-107, Jan.-Feb. 1995.
Article
in English
| LILACS
| ID: lil-319907
RESUMO
Mosquitoes are vector of serious human and animal diseases, such as malaria, dengue, yellow fever, among others. The use of biological control agents has provide an environmentally safe and highly specific alternative to the use of chemical insecticides in the control of vector borne diseases. Bacillus thuringiensis and B. sphaericus produce toxic proteins to mosquito larvae. Great progress has been made on the biochemical and molecular characterization of such proteins and the genes encoding them. Nevertheless, the low residuality of these biological insecticides is one of the major drawbacks. This article present some interesting aspects of the mosquito larvae feeding habits and review the attempts that have been made to genetically engineer microorganisms that while are used by mosquito larvae as a food source should express the Bacillus toxin genes in order to improve the residuality and stability in the mosquito breeding ponds.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Bacillus thuringiensis
/
Bacterial Toxins
/
Mosquito Control
/
Disease Vectors
Limits:
Animals
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
1995
Type:
Article
Affiliation country:
Colombia
Institution/Affiliation country:
Corporación para Investigaciones Biológicas/CO
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