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Compliance with pharmacological treatment in outpatients from a Brazilian cardiology referral center
Chizzola, Paulo Roberto; Mansur, Alfredo José; Luz, Protasio Lemos da; Bellotti, Giovanni.
  • Chizzola, Paulo Roberto; University of São Paulo. Hospital das Clinicas. Instituto do Coração. BR
  • Mansur, Alfredo José; University of São Paulo. Hospital das Clinicas. Instituto do Coração. BR
  • Luz, Protasio Lemos da; University of São Paulo. Hospital das Clinicas. Instituto do Coração. BR
  • Bellotti, Giovanni; University of São Paulo. Hospital das Clinicas. Instituto do Coração. BR
São Paulo med. j ; 114(5): 1259-1264, Sep.-Oct. 1996.
Article in English | LILACS | ID: lil-320855
ABSTRACT
To evaluate the degree of compliance with pharmacological therapy, and to identify predictors of non-compliance in outpatients from a cardiology referral center in São Paulo, Brazil, we studied 485 outpatients 230 (47.4 percent) males and 255 (52.6 percent) females, through an interview guided by a questionnaire during medical consultation. The ages ranged between 17 and 86 (mean 54, standard deviation 15) years. Heart disease and socioeconomic factors (residence, means of transport, educational level and professional status) were studied. In addition, we examined the drugs prescribed including difficulties in taking them; the source of supply, and the patient's knowledge of the drugs. Assessment of compliance was based on the patients' response. The patients' answers were compared with the prescription and progress notes. Errors were recorded if the patient reported using one or more nonprescribed medicines. Compliance with therapy was recorded if the patient said the prescription was taken correctly without interruption and without error. The variables with significant differences in univariate analysis were further analyzed by multivariate log-linear regression analysis. Noncompliance occurred in 286 (59 percent) of the patients, and was predicted by the reported difficulty in taking medication (P < 0.001), and by the lack of knowledge of medication names (P < 0.001). Thus, noncompliance with medical therapy was common. The main predictors of non-compliance were the reported difficulty in taking medication and inability to identify medicines' names.
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Cardiovascular Diseases / Patient Compliance Type of study: Observational study / Prognostic study / Qualitative research / Risk factors Limits: Adolescent / Adult / Aged80 / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: São Paulo med. j Journal subject: Cirurgia Geral / Ciˆncia / Ginecologia / Medicine / Medicina Interna / Obstetr¡cia / Pediatria / Sa£de Mental / Sa£de P£blica Year: 1996 Type: Article Affiliation country: Brazil Institution/Affiliation country: University of São Paulo/BR

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Full text: Available Index: LILACS (Americas) Main subject: Cardiovascular Diseases / Patient Compliance Type of study: Observational study / Prognostic study / Qualitative research / Risk factors Limits: Adolescent / Adult / Aged80 / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: São Paulo med. j Journal subject: Cirurgia Geral / Ciˆncia / Ginecologia / Medicine / Medicina Interna / Obstetr¡cia / Pediatria / Sa£de Mental / Sa£de P£blica Year: 1996 Type: Article Affiliation country: Brazil Institution/Affiliation country: University of São Paulo/BR