Concurrent cutaneous, visceral and ocular leishmaniasis caused by Leishmania (Viannia) braziliensis in a kidney transplant patient
Mem. Inst. Oswaldo Cruz
;
97(5): 751-753, July 2002. ilus
Article
in English
| LILACS
| ID: lil-321205
RESUMO
Although cases of leishmaniasis co-infection have been described in acquired immunodeficiency syndrome patients as well as those who have undergone organ transplants, to our knowledge, the present report is the first documented case of simultaneous cutaneous, visceral and ocular leishmaniasis due to Leishmania (Viannia) braziliensis in a transplant patient. The patient had been using immunosuppressive drugs since receiving a transplanted kidney. The first clinical signs of leishmaniasis included fever, thoracic pain, hepatosplenomegaly, leucopenia and anemia. The cutaneous disease was revealed by the presence of amastigotes in the skin biopsy. After three months, the patient presented fever with conjunctive hyperemia, intense ocular pain and low visual acuity. Parasites isolated from iliac crest, aqueous humor and vitreous body were examined using a range of molecular techniques. The same strain of L. (V.) braziliensis was responsible for the different clinical manifestations. The immunosuppressive drugs probably contributed to the dissemination of Leishmania
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Leishmania braziliensis
/
Eye Infections, Parasitic
/
Immunosuppression Therapy
/
Kidney Transplantation
/
Leishmaniasis, Cutaneous
/
Leishmaniasis, Visceral
Limits:
Animals
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2002
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Faculdade de Ciências Médicas de Minas Gerais/BR
/
Fiocruz/BR
/
UFMG/BR
/
Universidade do Estado de Minas Gerais/BR
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