Prevalence of hepatitis C Virus infection among hemophiliacs in Central Brazil
Mem. Inst. Oswaldo Cruz
;
97(5): 643-644, July 2002. tab
Article
in English
| LILACS
| ID: lil-321206
ABSTRACT
In order to investigate the hepatitis C virus (HCV) infection prevalence and risk factors in hemophiliacs in Central Brazil, 90 patients were interviewed and serum samples tested for HCV RNA and anti-HCV antibodies. An overall prevalence of 63.3 percent (CI 95 percent: 53.0-72.7) was found. Multivariate analysis of risk factors showed that number of blood transfusions was significantly associated with this infection. Most hemophiliacs received locally produced cryoprecipitate. All infected patients were transfused before the screening of blood units for anti-HCV. However, hemophiliacs who received exclusively screened cryoprecipitate were HCV negative. It confirms the expected decline in transfusion-acquired hepatitis C
Full text:
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Index:
LILACS (Americas)
Main subject:
Renal Dialysis
/
Hepatitis C
/
Hepatitis C Antibodies
Type of study:
Etiology study
/
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2002
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Fiocruz/BR
/
Universidade Federal de Goiás/BR
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