Study of chronic hemolytic anaemia patients in Rio de Janeiro: prevalence of anti-human parvovirus B19 IgG antibodies and the developement of transient aplastic crises
Rev. Inst. Med. Trop. Säo Paulo
;
44(4): 187-190, July-Aug. 2002. tab
Article
in English
| LILACS
| ID: lil-321219
RESUMO
The prevalence of anti-human parvovirus B19 IgG antibodies was determined in sera from 165 chronic hemolytic anemia patients, receiving medical care at Instituto Estadual de Hematologia (IEHE), Rio de Janeiro, during the year of 1994. This sample represents around 10 percent of the chronic hemolytic anemia patients attending at IEHE. Most of these patients (140) have sickle cell disease. Anti-B19 IgG antibodies were detected in 32.1 percent of patients. No statistically significant difference (p > 0.05) was seen between IgG antibody prevalence in male (27.8 percent) and female (35.5 percent) patients. Anti-B19 IgG antibodies were more frequent in older (37.6 percent) than younger (28.2 percent) than 20 years old patients, although this difference had no statistical significance (p > 0.05). Anti-B19 IgG antibody prevalence showed that 67.9 percent of patients enrolled in the study were susceptible to B19 acute infection. With the aim to detect acute B19 infection, patients follow up continued until February 1996. During this period four patients presented transient aplastic crisis due to human parvovirus B19 as confirmed by the detection of specific IgM antibodies. All four patients were younger than 20 years old, and 3 were younger than 10 years old. Three of them were sickle cell disease patients. Three of the four acute B19 infection occurred during 1994 springtime
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Parvovirus B19, Human
/
Parvoviridae Infections
/
Anemia, Aplastic
/
Anemia, Hemolytic
/
Antibodies, Viral
Type of study:
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Rev. Inst. Med. Trop. Säo Paulo
Journal subject:
Tropical Medicine
Year:
2002
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Instituto Oswaldo Cruz/BR
/
RJ+BR
/
UFF/BR
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