Rol de la teicoplanina en el tratamiento ambulatorio de infecciones causadas por microorganisamos grampositivos en niños / Role of teicoplanin in the ambulatory treatment of infections in children due to gram-positive microorganisms
Medicina (B.Aires)
;
62(supl.2): 48-51, 2002. tab
Article
in Spanish
| LILACS
| ID: lil-322242
ABSTRACT
Infections caused by Gram-positive bacteria remain a major cause of morbidity and mortality. Teicoplanin is a glycopeptide antibiotic with similar spectrum to vancomycin. Easy administration and dosage encourage its use in children, particularly due to its long half-life which allows single daily dose regimens. We evaluated the efficacy of teicoplanin in severe infections in children due to Gram-positive organisms. We retrospectively analyzed 171 children with proven or suspected Gram-positive infection treated with teicoplanin between January 1996 and December 2000. Of them, 166 cases were valuable for clinical assessment. Staphylococcus aureus (72) and coagulase-negative staphylococci (38) were the most frequent pathogens isolated. Osteoarthritis (35) and catheter-related infections (31) were the predominant clinical foci. The cure and improvement rates were 88 (150 patients) and 5 (9 patients) respectively. There were 7 (4) cases of therapeutic failure. Mean treatment duration was 10 +/- 34.3 days (range: 1-205). Adverse events were registered in 11 patients (6, 15 adverse events). In this study population, teicoplanin was safe and effective in the ambulatory treatment of severe Gram-positive infections in children
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Index:
LILACS (Americas)
Main subject:
Gram-Positive Bacterial Infections
/
Teicoplanin
/
Ambulatory Care
/
Anti-Bacterial Agents
Type of study:
Observational study
Limits:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
Spanish
Journal:
Medicina (B.Aires)
Journal subject:
Medicine
Year:
2002
Type:
Article
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