Hematological, biochemical and anatomopathological aspects of the experimental infection with Trypanosoma evansi in dogs
Arq. bras. med. vet. zootec
;
54(1): 8-18, fev. 2002. ilus
Article
in English
| LILACS
| ID: lil-324250
ABSTRACT
The course of experimental T. evansi infection in four dogs was followed for 82 days and hematological, biochemical and anatomopathological findings were studied. Infected animals showed progressive decrease in red blood cell count and hemoglobin concentration, leading to anemia which persisted from the third week post-infection until the end of the study. Leucopenia and neutropenia were observed between weeks 2 and 5 of the infection. The infected dogs developed hyperproteinemia and a decrease in the albuminglobulin ratio was observed. Aspartate aminotransferase and alamine aminotransferase levels increased significantly in infected dogs in comparison to control dogs. Histological changes observed in all infected animals consisted of lymphoid hyperplasia in spleens and lymph nodes and centrilobular degeneration and periportal mononuclear cell accumulation in the liver. A massive mononuclear cell infiltration of the myocardium was seen in three dogs and a nonsuppurative meningoencephalitis was evidente in two infected animals
Full text:
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Index:
LILACS (Americas)
Main subject:
Trypanosoma
/
Biochemistry
/
Hematology
Limits:
Animals
Language:
English
Journal:
Arq. bras. med. vet. zootec
Journal subject:
Veterinary Medicine
Year:
2002
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Estadual Paulista/BR
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