Baypamun® action in hamsters experimentally infected with Leptospira interrogans serogroup Canicola
Braz. j. vet. res. anim. sci
;
38(6): 293-295, 2001.
Article
in English
| LILACS
| ID: lil-324338
RESUMO
Baypamun® is an immunity modulator recommended as prophylactic and therapeutic use. In the present study, this product was used in the hamsters experimentally infected with Leptospira interrogans serogroup canicola. The animals were divided in 5 groups, with 20 animals each. This product was used as a therapeutic, prophylactic and as adjuvant. As a therapeutic use all the animals died. Despite of eight (40.0 percent) survivors, the prophylactic use wasn't also totally favorable due to leptospire recovering from kidneys of those animals. Based on the analysis of antibodies levels among animals that received vaccine and vaccine with Baypamun® as adjuvante, this product didn't conferred superior humoral answer. However, other studies should be accomplished utilizing this product in a longer period as well as verify the cellular answer by Baypamun® use as adjuvant in the infectious disease
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Adjuvants, Immunologic
/
Immunity
/
Leptospira interrogans
Limits:
Animals
Language:
English
Journal:
Braz. j. vet. res. anim. sci
Journal subject:
Veterinary Medicine
Year:
2001
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Estadual Paulista/BR
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