Decreased plasma angiotensin-converting enzyme activity in pregnancy-induced hypertension
Arch. venez. farmacol. ter
;
18(1): 39-42, 1999. tab, graf
Article
in English
| LILACS
| ID: lil-325669
ABSTRACT
Angiotensin converting enzyme (ACE) and aldosterone concentration were measured in the plasma of 32 pregnant women with normal blood pressure or with Pregnancy-induced hypertension (PIH). Mean arterial pressure (MAP) in PIH women was significantly higher than in normotensive pregnant women. Plasma ACE activity and aldosterone concentration in 17 PIH patients was significantly lower than their normotensive counterparts (15 cases). Mean arterial pressure was negatively correlated with the level of plasma ACE activity and with plasma aldosterone concentration in all pregnant women. Our results indicate that the circulating renin-angiotensin-aldosterone system is suppressed in pregnancy-induced hypertension
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Index:
LILACS (Americas)
Main subject:
Plasma
/
Pre-Eclampsia
/
Pregnancy Complications
/
Peptidyl-Dipeptidase A
/
Hypertension
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Pregnancy
Country/Region as subject:
South America
/
Venezuela
Language:
English
Journal:
Arch. venez. farmacol. ter
Journal subject:
Pharmacology
/
Therapeutics
Year:
1999
Type:
Article
Affiliation country:
Brazil
/
Venezuela
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