Experimental models of Schistosoma mansoni infection

Cheever, Allen W; Lenzi, Jane A; Lenzi, Henrique L; Andrade, Zilton A

Cheever, Allen W; Lenzi, Jane A; Lenzi, Henrique L; Andrade, Zilton A.

Cheever, Allen W; Biomedical Research Institute. US
Lenzi, Jane A; Fiocruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro. BR
Lenzi, Henrique L; Fiocruz. Instituto Oswaldo Cruz. Departamento de Patologia. Rio de Janeiro. BR
Andrade, Zilton A; Fiocruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador. BR

Mem. Inst. Oswaldo Cruz ; 97(7): 917-940, Oct. 2002. ilus, tab

Article in English | LILACS | ID: lil-325928

ABSTRACT

ABSTRACT

Experimental models of Schistosoma mansoni infections in mammals have contributed greatly to our understanding of the pathology and pathogenesis of infection. We consider here hepatic and extrahepatic disease in models of acute and chronic infection. Experimental schistosome infections have also contributed more broadly to our understanding of granulomatous inflammation and our understanding of Th1 versus Th2 related inflammation and particularly to Th2-mediated fibrosis of the liver

Subject(s)

Animals; Disease Models, Animal; Granuloma; Schistosoma mansoni; Schistosomiasis mansoni; Acute Disease; Chronic Disease; Granuloma; Liver; Mammals; Schistosomiasis mansoni; Th1 Cells; Th2 Cells

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Full text: Available Index: LILACS (Americas) Main subject: Schistosoma mansoni / Schistosomiasis mansoni / Disease Models, Animal / Granuloma Type of study: Systematic reviews Limits: Animals Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 2002 Type: Article Affiliation country: Brazil / United States Institution/Affiliation country: Biomedical Research Institute/US / Fiocruz/BR

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