Multicenter Brazilian study of oral Candida species isolated from Aids aatients
Mem. Inst. Oswaldo Cruz
;
97(2): 253-257, Mar. 2002. tab
Article
in English
| LILACS
| ID: lil-326279
ABSTRACT
Oropharyngeal candidiasis continues to be considered the most common opportunistic disease in Aids patients. This study was designed to investigate species distribution, serotype and antifungal susceptibility profile among Candida spp. isolated from the oral cavity of Aids patients recruited from six Brazilian university centers. Oral swabs from 130 Aids patients were plated onto CHROMagar Candida medium and 142 isolates were recovered. Yeast isolates were identified by classical methods and serotyped using the Candida Check« system-Iatron. Antifungal susceptibility testing was performed according to the NCCLS microbroth assay. C. albicans was the most frequently isolated species (91 percent), and 70 percent of the isolates belonged to serotype A. We detected 12 episodes of co-infection (9 percent), including co-infection with both serotypes of C. albicans. Non-albicans species were isolated from 12 episodes, 50 percent of them exhibited DDS or resistance to azoles. Otherwise, only 8 out 130 isolates of C. albicans exhibited DDS or resistance to azoles. Brazilian Aids patients are infected mainly by C. albicans serotype A, most of them susceptible to all antifungal drugs
Full text:
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Index:
LILACS (Americas)
Main subject:
Candida
/
Candidiasis, Oral
/
AIDS-Related Opportunistic Infections
/
Antifungal Agents
Type of study:
Controlled clinical trial
/
Observational study
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2002
Type:
Article
/
Project document
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal da Bahia/BR
/
Universidade Federal de Säo Paulo/BR
/
Universidade Federal de Uberlândia/BR
/
Universidade Federal do Paraná/BR
/
Universidade de Säo Paulo/BR
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