Pathogenesis of Salmonella-induced enteritis
Braz. j. med. biol. res
;
36(1): 03-12, Jan. 2003. ilus, tab
Article
in English
| LILACS
| ID: lil-326306
ABSTRACT
Infections with Salmonella serotypes are a major cause of food-borne diseases worldwide. Animal models other than the mouse have been employed for the study of nontyphoidal Salmonella infections because the murine model is not suitable for the study of Salmonella-induced diarrhea. The microbe has developed mechanisms to exploit the host cell machinery to its own purpose. Bacterial proteins delivered directly into the host cell cytosol cause cytoskeletal changes and interfere with host cell signaling pathways, which ultimately enhance disease manifestation. Recently, marked advances have been made in our understanding of the molecular interactions between Salmonella serotypes and their hosts. Here, we discuss the molecular basis of the pathogenesis of Salmonella-induced enteritis
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Salmonella Infections, Animal
/
Salmonella typhimurium
/
Diarrhea
/
Enteritis
Type of study:
Etiology study
/
Prognostic study
Limits:
Animals
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
2003
Type:
Article
/
Project document
Affiliation country:
Brazil
/
United States
Institution/Affiliation country:
Texas A&M University System/US
/
Texas A&M University/US
/
Universidade Federal de Minas Gerais/BR
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