Efecto de riesgo en el hijo de madre con edad avanzada (estudio de casos y controles) / Effect of risk on the child of an older mother (case-control study)
Ginecol. obstet. Méx
;
70(6): 295-302, jun. 2002.
Article
in Spanish
| LILACS
| ID: lil-331083
ABSTRACT
INTRODUCTION:
During the last decades the number of births in women with 35 or more years of age has increased approximately 35-50.OBJECTIVE:
To establish the neonatal morbidity associated with advanced maternal age, compared with mothers in the optimal reproductive stage. MATERIALS ANDMETHODS:
This is a retrospective case-control survey. In 1999 we revised 210 records from neonates and mothers with 35 or more years of age (cases) and 210 records of neonates and mothers with age between 18 and 34 years (controls). The variability significance was established with t-student, X2 and risk with the probabilistic risk ratio.RESULTS:
There was a significant difference in the socioeconomic and educational level. Advanced maternal age predisposed 2.43 times indication for cesarean section, increased the risk for gestational diabetes (11.35), toxemia (4.11) and in its severe form (2 times). Miscarriage menace (5.65 times). Lower birth weight (p < 0.007) and wet lung syndrome were more frequent in the advanced age group (p < 0.02). Risk for hypoglycemia was 1.62. There was also an increase in the risk for Trisomy 21 (p < 0.05) with an OR of 4 in cases. Genetic service evaluated 35 patients in the maternal advanced age group with an OR of 35.CONCLUSIONS:
Advance maternal age increases maternal morbidity and the risk for preterm delivery, low birth weight, asymptomatic hypoglycemia, wet lung syndrome and risk for chromosomopathies.
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Index:
LILACS (Americas)
Main subject:
Pregnancy Outcome
/
Maternal Age
/
Infant, Newborn, Diseases
Type of study:
Etiology study
/
Observational study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Infant, Newborn
/
Pregnancy
Country/Region as subject:
Mexico
Language:
Spanish
Journal:
Ginecol. obstet. Méx
Journal subject:
Gynecology
/
Obstetrics
Year:
2002
Type:
Article
Affiliation country:
Mexico
Institution/Affiliation country:
Instituto Nacional de Perinatología/MX
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