Cambios ultrasonográficos y en lípidos en el síndrome de ovario poliquÝstico de acuerdo al tipo de tratamiento / Ultrasonographic and lipid changes in polycystic ovary syndrome according to the type of treatment
Ginecol. obstet. Méx
;
70(6): 285-288, jun. 2002.
Article
in Spanish
| LILACS
| ID: lil-331085
RESUMO
OBJECTIVE: To determine the ultrasonographic and lipid changes in women with polycystic ovary syndrome (PCOS) according to the type of hormonal treatment. STUDY DESIGN: Thirty-two women with clinical and ultrasonographic diagnosis of PCOS were studied and randomly distributed in one or another treatment group. Group I: chlormadinone (2 mg/day for 5 days every month) (n = 16) and Group II: ethinylestradiol 35 micrograms plus desogestrel 150 mg (21 days every month) (n = 16). At baseline and at third month a pelvic ultrasound was done to assess the number and size of follicles, also total cholesterol and triglycerides were measured. RESULTS: In both groups a significant decrease was found in the number of follicles in both ovaries, but only in group II there was a significant decrease in follicular size in both ovaries. No differences were found between the groups in the number of follicles or in the final follicular size. In both groups, a significant decrease was found in total cholesterol levels, without changes in triglycerides levels. CONCLUSION: Only combined therapy decreased follicular size. So the type of treatment should be based on patient expectations such as sexual activity, or for control of androgen excess.
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Index:
LILACS (Americas)
Main subject:
Polycystic Ovary Syndrome
/
Progestins
/
Triglycerides
/
Chlormadinone Acetate
/
Cholesterol
/
Desogestrel
/
Estradiol Congeners
/
Ethinyl Estradiol
Limits:
Adult
/
Female
/
Humans
Language:
Spanish
Journal:
Ginecol. obstet. Méx
Journal subject:
Gynecology
/
Obstetrics
Year:
2002
Type:
Article
Affiliation country:
Mexico
Institution/Affiliation country:
Instituto Mexicano del Seguro Social/MX
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