Rheumatic fever and HLA antigens
Medicina (Ribeiräo Preto)
; 33(1): 55-59, jan.-mar. 2000. tab
Article
in En
| LILACS
| ID: lil-331504
Responsible library:
BR26.1
ABSTRACT
In this study we typed HLA class I and II antigens in a series of patients presenting with the distinct major clinical manifestations of rheumatic fever (RF), i.e, chorea, carditis or arthritis. Ninety-one patients with RF were evaluated for HLA-A, -B and -DR antigens. Thirty-three had pure chorea, 26 pure carditis, 16 pure arthritis, and 16 carditis plus arthritis. HLA-DR1 antigens were overrepresented in the total group of patients with RF and in all the subgroups studied, excluding the chorea subgroup in which the frequency of HLA-DR1 antigen was not increased. The results reported here indicate that immunogenetic susceptibility to RF may vary according to the major clinical manifestations presented by the patient
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Index:
LILACS
Main subject:
Rheumatic Fever
/
HLA Antigens
Limits:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
Language:
En
Journal:
Medicina (Ribeiräo Preto)
Journal subject:
MEDICINA
Year:
2000
Type:
Article