Impacto de la dieta sobre la inducción de infección con quistes de Giardia lamblia en ratas Sprague-Dawley / Impact of diet on the induction of infection with Giardia lamblia cysts in Sprague-Dawley rats
Salud pública Méx
;
44(4): 315-322, jul.-aug. 2002.
Article
in Spanish
| LILACS
| ID: lil-331710
RESUMEN
OBJECTIVE:
To assess the effect of malnutrition on the development of giardiasis in Sprague-Dawley rats, using different inoculum sizes of Giardia lamblia cysts. MATERIAL ANDMETHODS:
An experimental study was conducted between 1995 and 1999 at Centro de Investigación, Alimentación y Desarrollo (Center for Research, Food, and Development), in Hermosillo, Sonora, Mexico. The study population consisted of two groups of six to eight experimental units that were fed two different diets and inoculated five different concentrations of Giardia lamblia cysts. Data were collected on excretion of cysts, weight gain, food intake, bowel contents, and macro and microscopic lesions in the intestinal mucosa. Statistical analysis consisted of analysis of variance and residuals.RESULTS:
Animals fed with a diet meeting nutritional requirements required an infecting inoculum of 60 cysts, while malnourished rats required only six cysts to develop mucosal lesions.CONCLUSIONS:
Weight gain monitored during ten days was not a good indicator of Giardia lamblia infection. Infection depended on cyst inoculum size as well as on the nutritional status of the tested animals.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Protein Deficiency
/
Giardiasis
/
Giardia lamblia
/
Diet
Limits:
Animals
Language:
Spanish
Journal:
Salud pública Méx
Journal subject:
Public Health
Year:
2002
Type:
Article
Affiliation country:
Mexico
Institution/Affiliation country:
Centro de Investigación en Alimentación y Desarrollo/MX
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