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Imunoblot como teste suplementar para detecção de anticorpos contra o vírus da hepatite C em doadores de sangue / Immunoblot as a supplemental test to detect antibodies to hepatitis C virus in blood donors
Souto, Francisco José; Ribeiro, Luciano Corrêa; Perazolo, Gustavo Faria; Fortes, Hildenete Monteiro; Saldanha, Alzira Almeida.
  • Souto, Francisco José; Universidade Federal do Mato Grosso. Núcleo de Estudos de Doenças Infecciosas e Tropicais. Cuiabá. BR
  • Ribeiro, Luciano Corrêa; Universidade Federal do Mato Grosso. Núcleo de Estudos de Doenças Infecciosas e Tropicais. Cuiabá. BR
  • Perazolo, Gustavo Faria; Universidade Federal do Mato Grosso. Núcleo de Estudos de Doenças Infecciosas e Tropicais. Cuiabá. BR
  • Fortes, Hildenete Monteiro; Universidade Federal do Mato Grosso. Núcleo de Estudos de Doenças Infecciosas e Tropicais. Cuiabá. BR
  • Saldanha, Alzira Almeida; Universidade Federal do Mato Grosso. Núcleo de Estudos de Doenças Infecciosas e Tropicais. Cuiabá. BR
Rev. Soc. Bras. Med. Trop ; 35(1): 69-71, jan.-fev. 2002.
Article in Portuguese | LILACS | ID: lil-331773
ABSTRACT
Supplemental tests using Immunoblot are recommended to improve specificity of anti-HCV by ELISA. In Brazil immunoblot is not officially recommended. Aiming to identify EIA false-positive rate 70 positive EIA anti-HCV blood donors were submitted to 3rd generation immunoblot at Hemocentro of Mato Grosso State where polymerase chain reaction tests are not performed. There were 44 (62.9) immunoblot-positive, 22 (31.4) negative and 4 (5.7) indeterminate. Anti-HCV immunoblot can distinguish blood donors with false-positive ELISA from those who need medical assessment. Our data suggest that immunoblot could be useful in Brazilian blood banks where molecular biology tests are not available.
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Full text: Available Index: LILACS (Americas) Main subject: Blood Donors / Immunoblotting / Hepatitis C Antibodies Limits: Humans Language: Portuguese Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2002 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Mato Grosso/BR

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Full text: Available Index: LILACS (Americas) Main subject: Blood Donors / Immunoblotting / Hepatitis C Antibodies Limits: Humans Language: Portuguese Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2002 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Mato Grosso/BR