Epidemiologic models to develop new research on human mycoses

RESUMO

We propose to apply a new sub model of the case-control-community-based epidemiologic design as a model to biomedical and epidemiologic research aimed to develop advanced and holistic research on human deep or localized mycoses transmitted from environment-to-man, in addition to classic or empirical epidemiologies, which by them selves are suitable to develop research on cutaneous, nail, or ocular mycoses. Our own contribution to complement and enhance research on deep and localized mycoses is the multidisciplinary family-case biomedical and epidemiologic model very useful to carry out biomedical and epidemiologic research on pathogenic deep and localized mycoses infections or diseases in man. In fact, the multidisciplinary family-case epidemiologic approach would also be a powerful for comprehensive research studies on chronic infections and syndromes asociated to paracoccidioidomycosis, chromomycosis, coccidioidomycosis, sporotrichosis, eumycetoma and actinomycetoma. The common starting point of such to be follewed in order to study any of those mycoses is based on a nested group of cases which have been previously well-defined as clinical deep mycotic patients from any of the research groups in Latin American countries. African countries, India, etc. Two control groups will allow to make best inferences: a) relatives face of clinical disease living in the same household of each cases (group # 1); b) adults living in other neighbor household where clinical cases of the specific deep mycoses studied has never appeared. In successful, results of application of this model would be established as standards to estimate prevalence and incidence of environment-to-man transmitted infections. That would means, potential application to reach primary and secondary prevention to improve local or regional public health, at least in South America