Human papillomavirus prevalence, viral load and cervical intraepithelial neoplasia in HIV-infected women
Braz. j. infect. dis
;
6(3): 129-135, Jun. 2002.
Article
in English
| LILACS, SES-SP
| ID: lil-332322
ABSTRACT
HIV-infected women from S o Paulo city were enrolled in a cross-sectional study on Human Papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN) prevalence and their association with laboratory markers of AIDS, namely HIV viral load and CD(4)(+) cell counts. A cervical specimen was collected and submitted to Hybrid Capture, a test for HPV viral load determination. HPV-DNA was detected in 173 of 265 women (64.5). Twenty (7.5) women were infected by one or more low-risk viruses, 89 (33) by one or more high-risk viruses, and 64 (24) harbored at least one HPV type from each risk group. Abnormal smears were observed in 19 of the patients, though there were no invasive carcinomas. Severely immunosuppressed patients (CD(4)/microL <100) were at the greatest risk of having a cytological abnormality and a high high-risk HPV viral load.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Tumor Virus Infections
/
HIV Infections
/
Uterine Cervical Neoplasms
/
Viral Load
/
Papillomavirus Infections
Type of study:
Etiology study
/
Observational study
/
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Female
/
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Braz. j. infect. dis
Year:
2002
Type:
Article
Institution/Affiliation country:
Casa da AIDS/BR
/
Digene do Brasil/BR
/
Emilio Ribas Institute/BR
/
Institute of Tropical Medicine/BR
/
University of São Paulo/BR
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