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New evidence of spontaneous cure in human Chagas' disease
Francolino, Sonia S; Antunes, Antonio Fernandez; Talice, Rodolfo; Rosa, Rachel; Selanikio, Joel; Rezende, Joffre Marcondes de; Romanha, Alvaro J; Dias, João Carlos Pinto.
  • Francolino, Sonia S; Blood Bank. Paysandu. UY
  • Antunes, Antonio Fernandez; s.af
  • Talice, Rodolfo; National University. Montevideo. UY
  • Rosa, Rachel; Chagas Disease Control Program. Montevideo. UY
  • Selanikio, Joel; CDC. Atlanta. US
  • Rezende, Joffre Marcondes de; Federal University of Goiás. Goiânia. BR
  • Romanha, Alvaro J; Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte. BR
  • Dias, João Carlos Pinto; Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte. BR
Rev. Soc. Bras. Med. Trop ; 36(1): 103-107, jan.-fev. 2003. ilus, tab
Article in English | LILACS | ID: lil-332893
RESUMO
A new case of spontaneous cure of human Chagas' disease is described in Uruguay. An 87-year-old man who had a typical acute phase of Trypanosoma cruzi infection in 1947 and never received specific treatment against the disease, when examined in 1998 revealed several completely negative parasitological and serological tests, including traditional serology, PCR and flow cytometry. As a whole, such findings fulfill the current criteria to define the cure of Chagas' disease. Clinical data suggest the possibility of a benign evolution of Chagas' disease in this case, but the basic findings (slight cardiac and esophageal impairment) could also be due to the advanced age of the patient
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Chagas Disease Limits: Aged / Aged80 / Humans / Male Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2003 Type: Article Affiliation country: Brazil / United States / Uruguay Institution/Affiliation country: Blood Bank/UY / CDC/US / Chagas Disease Control Program/UY / Federal University of Goiás/BR / Fundação Oswaldo Cruz/BR / National University/UY

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Full text: Available Index: LILACS (Americas) Main subject: Chagas Disease Limits: Aged / Aged80 / Humans / Male Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2003 Type: Article Affiliation country: Brazil / United States / Uruguay Institution/Affiliation country: Blood Bank/UY / CDC/US / Chagas Disease Control Program/UY / Federal University of Goiás/BR / Fundação Oswaldo Cruz/BR / National University/UY