Nicaraguan population data on LDLR, GYPA, D7S8, HBGG, GC and HLA-DQA1 loci
Rev. biol. trop
;
49(3/4): 1253-1260, Sep.-Dec. 2001.
Article
in English
| LILACS
| ID: lil-333060
ABSTRACT
Nicaraguans have become the most numerous and fastest increasing minority in Costa Rica: at present they represent around 6 of the total population of the country. We have analyzed the allele and genotype frequencies of six PCR-based genetic markers (LDLR, GYPA, HBGG, D7S8, GC, and HLA-DQA1) in 100 unrelated Nicaraguans living in Costa Rica. All loci studied were in Hardy-Weinberg equilibrium. Some statistical parameters of forensic interest were also calculated (h, PD and CE). Allele frequencies of the markers HLA-DQA1 and GYPA were found to be significantly different between the populations of Nicaragua and Costa Rica. Nevertheless, genetic distances showed that Nicaragua is close to other Hispanic-admixed populations like those from Argentina, Chile, Colombia, Costa Rica, and USA Hispanics. The loci set was assessed to be useful for paternity testing and individual identification in the Nicaraguan population residing in Costa Rica.
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Index:
LILACS (Americas)
Main subject:
Genetic Markers
/
Gene Frequency
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
Central America
/
Costa Rica
/
Nicaragua
Language:
English
Journal:
Rev. biol. trop
Journal subject:
Biology
/
Tropical Medicine
Year:
2001
Type:
Article
Affiliation country:
Costa Rica
/
Spain
Institution/Affiliation country:
Universidad de Costa Rica/CR
/
Universitat Pompeu Fabra/ES
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