Deficiencia de folato y concentraciones elevadas de formato en suero y líquido cefalorraquídeo de pacientes con neuropatía óptica epidémica / Folic acid deficiency and increased concentrations of formate in serum and cerebrospinal fluid of patients with epidemic optical neuropathy
Rev. cuba. med. trop
; 52(1): 21-23, Jan.-Apr. 2000.
Article
in Es
| LILACS
| ID: lil-333502
Responsible library:
BR1.1
RESUMEN
We studied 62 patients aged 48 years as an average and diagnosed with bilateral optical neuropathy during an epidemics in Pinar del RÝo province. Of these patients, 42 showed the optical form whereas 20 had the mixed form of optical neuropathy. We researched into the levels of formate and folate in serum and cerebrospinal fluid samples and we found a marked deficiency of folates in more than 50 of samples and high formate concentration levels in almost 25 of samples. We concluded that nutritional shortages that lead to a reduction of folates, and the intake of small amounts of methanol in alcoholic drinks could lead to lacking energetic states which would facilitate that the optical nerve be affected and the epidemic optical neuropathy appear.
Full text:
1
Index:
LILACS
Main subject:
Optic Nerve Diseases
/
Disease Outbreaks
/
Folic Acid
/
Folic Acid Deficiency
/
Formates
Type of study:
Etiology_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Male
Language:
Es
Journal:
Rev. cuba. med. trop
Journal subject:
MEDICINA TROPICAL
Year:
2000
Type:
Article