Endocarditis verrucosa secundaria a saccharomyces cerevisiae: caso clínico / Saccharomyces cerevisiae endocarditis in a preterm infant: report of one case
Rev. méd. Chile
;
130(10): 1165-1169, oct. 2002.
Article
in Spanish
| LILACS
| ID: lil-339180
RESUMO
We report a preterm infant with 30 weeks of gestation, that received broad spectrum antimicrobials during the first days of life. At nine days of life, the infant appeared with abdominal distension and hematochezia. A systolic murmur with changing auscultatory features also appeared. An echocardiography showed an atrial vegetation. A yeast, that was identified as the emergent pathogen Saccharomyces cerevisiae appeared in two blood cultures. Treatment with amphotericin B was started, the dose was adjusted calculating the minimal inhibitory concentration of amphotericin B, and measuring plasma levels of the antimicrobial. Therefore the minimal effective dose was prescribed, avoiding its deleterious effects. After 14 days of antifungal therapy, a new echocardiography showed a reduction in the size of the atrial vegetation. At 35 days, it disappeared and amphotericin B was discontinued. On the outpatient follow up, the infant has shown a normal growth and a normal cardiac auscultation
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Saccharomyces cerevisiae
/
Endocarditis, Bacterial
Type of study:
Etiology study
Limits:
Humans
/
Male
/
Infant, Newborn
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2002
Type:
Article
Affiliation country:
Colombia
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