Your browser doesn't support javascript.
loading
Production and supply of high specific activity radioisotopes for radiotherapy applications
Ketring, A. R; Ehrhardt, G. J; Embree, M. F; Bailey, K. D; Tyler, T. T; Gawenis, J. A; Jurisson, S. S; Engelbrecht, H. P; Smith, C. J; Cutler, C. S.
Affiliation
  • Ketring, A. R; University of Missouri Reasearch Reactor.
  • Ehrhardt, G. J; University of Missouri Reasearch Reactor.
  • Embree, M. F; University of Missouri Reasearch Reactor.
  • Bailey, K. D; University of Missouri Reasearch Reactor.
  • Tyler, T. T; University of Missouri Reasearch Reactor.
  • Gawenis, J. A; University of Missouri Reasearch Reactor.
  • Jurisson, S. S; University of Missouri Reasearch Reactor.
  • Engelbrecht, H. P; University of Missouri Reasearch Reactor.
  • Smith, C. J; University of Missouri Reasearch Reactor.
  • Cutler, C. S; University of Missouri Reasearch Reactor.
Rev. med. nucl. Alasbimn j ; 5(19)ene. 2003.
Article in En | LILACS | ID: lil-339345
Responsible library: CL1.1
RESUMO
High specific activity radioisotopes such as Lu-177, Pm-149, Ho-166 and Rh-105 can be produced by indirect methods involving neutron irradiation of isotopically enriched (e.g. Ru-104) targets producing parent radioisotopes that beta decay to form the desired daughter radioisotopes. For example, Lu-177 can be produced by direct (n, gamma) irradiation of Lu-176. However, only about 20 percent of the Lu-176 atoms are converted to Lu-177 and the long-lived impurity Lu-177m (half-life = 160 days) is also produced in small quantities. Direct irradiation of Yb-176 results in the production of Yb-177 (half-life = 1.9 hr) that beta decays to form Lu-177, with the further advantage that this route of production avoids long-lived Lu-177m. Chemical separation of the Lu-177 from the Yb target results in a high specific activity Lu-177 that can then be used for radiotherapy. Separation of Rh-105 from irradiated Ru-104 targets is also being investigated by volatilization of the Ru
Subject(s)
Fulltext
Add to My VHL
Print
XML
Search on Google
Full text: 1 Index: LILACS Main subject: Radioisotopes / Radiotherapy Limits: Humans Language: En Journal: Rev. med. nucl. Alasbimn j Journal subject: MEDICINA NUCLEAR Year: 2003 Type: Article
Fulltext
Add to My VHL
Print
XML
Search on Google
Full text: 1 Index: LILACS Main subject: Radioisotopes / Radiotherapy Limits: Humans Language: En Journal: Rev. med. nucl. Alasbimn j Journal subject: MEDICINA NUCLEAR Year: 2003 Type: Article