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Herpes simples virus ophthalmic disease induced using two different methods of mice inoculation
Pereira, Silvia Regina Ferreira Gonçalves; Guimaräes, Maria Angélica A. M; V. Neto, Leonardo; Segenreich, Daniel; Varella, Rafael Brandäo; Chagas, Vera Lucia Antunes; Câmara, Fernando Portela.
Affiliation
  • Pereira, Silvia Regina Ferreira Gonçalves; s.af
  • Guimaräes, Maria Angélica A. M; s.af
  • V. Neto, Leonardo; s.af
  • Segenreich, Daniel; s.af
  • Varella, Rafael Brandäo; s.af
  • Chagas, Vera Lucia Antunes; s.af
  • Câmara, Fernando Portela; s.af
Braz. j. infect. dis ; 5(4): 183-191, Aug. 2001. ilus
Article in En | LILACS | ID: lil-339408
Responsible library: BR11.1
ABSTRACT
Two different procedures for inoculation of HSV on corneas of balb/c mice were evaluated. The first was by the use of HSV suspensions directly on the corneas and the other was after corneal scarification. Animals by this later method presented greater morbidity and mortalitythan those of first group, suggesting than inoculation of HSV without scarification of the cornea should be the method of choice for the study of HSV ophthalmic infection. This model showed also be an efficient experimental system to testing antiviral drugs.
Subject(s)
Full text: 1 Index: LILACS Main subject: Eye Infections / Keratitis, Herpetic / Simplexvirus / Cornea / Mice, Inbred BALB C Limits: Animals Language: En Journal: Braz. j. infect. dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2001 Type: Article
Full text: 1 Index: LILACS Main subject: Eye Infections / Keratitis, Herpetic / Simplexvirus / Cornea / Mice, Inbred BALB C Limits: Animals Language: En Journal: Braz. j. infect. dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2001 Type: Article