Lactate dehydrogenase isoenzymes in dental pulp of rats according to stage of root development
Braz. dent. j
;
14(1): 5-11, June 2003. tab, graf
Article
in English
| LILACS
| ID: lil-340481
RESUMO
The objective of this study was to present a classification of the root development stage of female rat molar teeth and to evaluate the variation in the lactate dehydrogenase (LDH) activity and electrophoretic isoenzyme profile according to the stage of root development of the molar teeth. We also studied the LDH activity and isoenzymes of the pulp of incisor teeth. The stage of development of the rat first molar at the age of 15 days and that of the second molar at the age of 18 days was classified as the beginning of root formation. At the age of 15 days, the electrophoretic profile of the isoenzymes for the first molar showed a prevalence of LDH-1 followed by LDH-2. However, for the maxillary second molar there was a prevalence of LDH-4 followed by LDH-1, while for the mandibular second molar LDH-1 predominated followed by LDH-2 and LDH-4. From 18 days of age, the prevalence was always of LDH-1. The electrophoretic profile of LDH isoenzymes from the pulp of the incisor teeth at the ages studied (25 and 60 days) showed the following order of prevalence LDH-1 > LDH-2 > LDH-3 > LDH-4 > LDH-5. These results suggest that there are variations in the prevalence of the various forms of LDH isoenzymes in the dental pulp of rats according to the developmental stage of the root
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Index:
LILACS (Americas)
Main subject:
Tooth Root
/
Dental Pulp
/
Isoenzymes
/
L-Lactate Dehydrogenase
/
Odontogenesis
Type of study:
Risk factors
Limits:
Animals
Language:
English
Journal:
Braz. dent. j
Journal subject:
Dentistry
Year:
2003
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Federal University of Paraná/BR
/
University of São Paulo/BR
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