Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
Mem. Inst. Oswaldo Cruz
;
98(4): 461-463, June 2003. ilus, tab
Article
in English
| LILACS
| ID: lil-344235
RESUMO
We analyzed, by env and gag heteroduplex mobility assay, 149 human immunodeficiency virus (HIV-1) positive samples collected in Ceará during the year 2000. The prevalence of subtype B was 81.2 percent and the prevalence of subtype F and B/F recombinants were both 2.7 percent. Eight (5.4 percent) and 12 (8 percent) out of 149 samples showed indeterminate results in the env and gag analysis respectively. By FokI restriction fragment length polymorphism, 34 percent of the subtype B samples were identified as the typical Brazilian subtype B.In the present study, we identified HIV-1 subtype F and B/F in Ceará for the first time. Our results contribute to the understanding of HIV in Brazil, and may prove useful for the development of vaccine candidates
Full text:
Available
Index:
LILACS (Americas)
Main subject:
DNA, Viral
/
Genes, env
/
Genes, gag
/
HIV Infections
/
HIV-1
Type of study:
Prevalence study
/
Risk factors
/
Screening study
Limits:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2003
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Fiocruz/BR
/
Fundação para o Desenvolvimento das Ciências/BR
/
Laboratório Central de Saúde Pública/BR
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