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Cyclic 3'-5' guanosine monophosphate-dependent activity in Leishmania amazonensis
Géigel, Lf; Leon, Ll.
  • Géigel, Lf; Instituto de Medicina Tropical Pedro Kourí. Departamento de Parasitología. Ciudad Habana. CU
  • Leon, Ll; Fiocruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro. BR
Mem. Inst. Oswaldo Cruz ; 98(4): 499-500, June 2003. graf
Article in English | LILACS | ID: lil-344242
ABSTRACT
Although there are some data concerning the nitric oxide and the cyclic 3'-5'guanosine monophosphate (cGMP) signaling pathway in trypanosomatids, there is no report about the cGMP-dependent enzymatic activity identification. In this sense, a cGMP dependent activity was detected on soluble fraction from Leishmania amazonensis promastigotes with a high metacyclic level. This information is valuable in order to explore the metabolic pathway of G kinase protein in this parasite
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Leishmania mexicana / Cyclic GMP-Dependent Protein Kinases Limits: Animals Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 2003 Type: Article Affiliation country: Brazil / Cuba Institution/Affiliation country: Fiocruz/BR / Instituto de Medicina Tropical Pedro Kourí/CU

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Full text: Available Index: LILACS (Americas) Main subject: Leishmania mexicana / Cyclic GMP-Dependent Protein Kinases Limits: Animals Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 2003 Type: Article Affiliation country: Brazil / Cuba Institution/Affiliation country: Fiocruz/BR / Instituto de Medicina Tropical Pedro Kourí/CU