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Antibody isotype responses in Balb/c mice immunized with the cytoplasmic repetitive antigen and flagellar repetitive antigen of Trypanosoma cruzi
Pereira, Valéria R. A; Lorena, Virginia Maria B; Verçosa, Alinne Fernanda A; Silva, Edmilson D; Ferreira, Antonio G. P; Montarroyos, Ulisses R; Silva, Ana P. Galao; Gomes, Yara M.
  • Pereira, Valéria R. A; Fiocruz. Centro de Pesquisas Aggeu Magalhäes. Departamento de Imunologia and Departamento de SaudeáColetiva. Recife. BR
  • Lorena, Virginia Maria B; Fiocruz. Centro de Pesquisas Aggeu Magalhäes. Departamento de Imunologia and Departamento de SaudeáColetiva. Recife. BR
  • Verçosa, Alinne Fernanda A; Fiocruz. Centro de Pesquisas Aggeu Magalhäes. Departamento de Imunologia and Departamento de SaudeáColetiva. Recife. BR
  • Silva, Edmilson D; Fiocruz. Biomanguinhos. Departamento de Reativos. Rio de Janeiro. BR
  • Ferreira, Antonio G. P; Fiocruz. Biomanguinhos. Departamento de Reativos. Rio de Janeiro. BR
  • Montarroyos, Ulisses R; Fiocruz. Centro de Pesquisas Aggeu Magalhäes. Departamento de Imunologia and Departamento de SaudeáColetiva. Recife. BR
  • Silva, Ana P. Galao; Universidade Federal de Pernambuco. Departamento de Patologia. Recife. BR
  • Gomes, Yara M; Fiocruz. Centro de Pesquisas Aggeu Magalhäes. Departamento de Imunologia and Departamento de SaudeáColetiva. Recife. BR
Mem. Inst. Oswaldo Cruz ; 98(6): 823-825, Sept. 2003. graf
Article in English | LILACS | ID: lil-348353
ABSTRACT
In the present report we analyzed the levels of IgG1, IgG2a, IgG2b and IgG3 isotypes from Balb/c mice immunized with cytoplasmic repetitive antigen (CRA), and flagelar repetitive antigen (FRA) of Trypanosoma cruzi. The immunization was done by subcutaneous route three times (20 days apart) and the analysis was performed 14 days after each treatment. CRA-immunized mice produced high levels of all IgG isotypes, mainly IgG3 and IgG1. FRA-immunization elicited only high levels of IgG1
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Full text: Available Index: LILACS (Americas) Main subject: Trypanosoma cruzi / Immunoglobulin Isotypes Limits: Animals Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 2003 Type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: Fiocruz/BR / Universidade Federal de Pernambuco/BR

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Full text: Available Index: LILACS (Americas) Main subject: Trypanosoma cruzi / Immunoglobulin Isotypes Limits: Animals Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 2003 Type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: Fiocruz/BR / Universidade Federal de Pernambuco/BR