Neurocortical electrical activity tomography in chronic schizophrenics
Arq. neuropsiquiatr
; Arq. neuropsiquiatr;61(3B): 712-717, Sept. 2003. ilus, tab
Article
in En
| LILACS
| ID: lil-348647
Responsible library:
BR1.1
RESUMO
Functional imaging of brain electrical activity was performed in 25 chronic medicated schizophrenics and 40 controls, analyzing the classical frequency bands (delta, theta, alpha, and beta) of 19-channel EEG during resting state to identify brain regions with deviant activity of different functional significances, using LORETA (Low Resolution Tomography) and SPM99 (Statistical Parametric Mapping). Patients differed from controls due to an excess of slow activity comprising delta + theta frequency bands (inhibitory pattern) located at the right middle frontal gyrus, right inferior frontal gyrus, and right insula, as well as at the bilateral anterior cingulum with a left preponderance. The high temporal resolution of EEG enables the specification of the deviations not only as an excess or a deficit of brain electrical activity, but also as inhibitory (delta, theta), normal (alpha), and excitatory (beta) activities. These deviations point out to an impaired functional brain state consisting of inhibited frontal and prefrontal areas that may result in inadequate treatment of externally or internally generated information
Full text:
1
Index:
LILACS
Main subject:
Schizophrenia
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Brain
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Brain Mapping
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Magnetoencephalography
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Electroencephalography
Type of study:
Observational_studies
Limits:
Adult
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Female
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Humans
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Male
Language:
En
Journal:
Arq. neuropsiquiatr
Journal subject:
NEUROLOGIA
/
PSIQUIATRIA
Year:
2003
Type:
Article