Leptomeningeal dissemination of pilocytic astrocytoma at diagnosis in childhood: two cases report
Arq. neuropsiquiatr
;
61(3B): 842-847, Sept. 2003. ilus, tab
Article
in English
| LILACS
| ID: lil-348680
RESUMO
Pilocytic astrocytoma (PA) is a benign tumor that rarely spread along the neuraxis. At the moment there are no more than five cases of leptomeningeal dissemination (LD) from PA at diagnosis described in the literature. Different patterns of presentation or recurrence may be noted local recurrence, malignant transformation, multicentric disease or metastatic disease. LD and multicentric disease can be distinct pathological entities. We report two cases and analyse literature, emphasizing leptomeningeal spread at presentation. Hydrocephalus, biopsy and parcial ressection are likely to be favorable factors to the occurrence of LD. Otherwise, LD may be part of natural history of PA, as evidenced by its ocurrence in non-treated cases
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Astrocytoma
/
Cerebellar Neoplasms
/
Meningeal Neoplasms
Type of study:
Diagnostic study
Limits:
Child
/
Female
/
Humans
Language:
English
Journal:
Arq. neuropsiquiatr
Journal subject:
Neurology
/
Psychiatry
Year:
2003
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Säo Paulo University/BR
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