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Mulheres alcoolistas: alterações eletrocardiográficas e distúrbios metabólicos e eletrolíticos associados / Female alcoholics: electrocardiographic changes and associated metabolic and electrolytic disorders
Borini, Paulo; Terrazas, José Henrique Imaca; Ferreira Júnior, Arlindo; Guimarães, Romeu Cardoso; Borini, Sabrina Bicalho.
  • Borini, Paulo; Hospital Espírita de Marília. Marília. BR
  • Terrazas, José Henrique Imaca; Hospital Espírita de Marília. Marília. BR
  • Ferreira Júnior, Arlindo; Hospital Espírita de Marília. Marília. BR
  • Guimarães, Romeu Cardoso; Hospital Espírita de Marília. Marília. BR
  • Borini, Sabrina Bicalho; Hospital Espírita de Marília. Marília. BR
Arq. bras. cardiol ; 81(5): 506-517, nov. 2003. tab
Article in English, Portuguese | LILACS | ID: lil-351137
RESUMO

OBJECTIVE:

To identify the electrocardiographic changes and their associations with metabolic and electrolytic changes in female alcoholics.

METHODS:

The study comprised 44 female alcoholics with no apparent physical disorder. They underwent the following examinations conventional electrocardiography; serologic tests for syphilis, Chagas' disease, and hepatitis B and C viruses; urinary pregnancy testing; hematimetric analysis; biochemical measurements of albumin, fibrinogen, fasting and postprandial glycemias, lipids, hepatic enzymes, and markers for tissue necrosis and inflammation.

RESULTS:

Some type of electrocardiographic change was identified in 33 (75 percent) patients. In 17 (38.6 percent) patients, more than one of the following changes were present prolonged QTc interval in 24 (54.5 percent), change in ventricular repolarization in 11(25 percent), left ventricular hypertrophy in 6 (13.6 percent), sinus bradycardia in 4 (9.1 percent), sinus tachycardia in 3 (6.8 percent), and conduction disorder in 3 (6.8 percent). The patients had elevated mean serum levels of creatine phosphokinase, aspartate aminotransferases, and gamma glutamyl transferase, as well as hypocalcemia and low levels of total cholesterol and LDL-cholesterol. The patients with altered electrocardiograms had a more elevated age, a lower alcohol consumption, hypopotassemia, and significantly elevated levels of triglycerides, postprandial glucose, sodium and gamma glutamyl transferase than those with normal electrocardiograms. The opposite occurred with fasting glycemia, magnesium, and alanine aminotransferase.

CONCLUSION:

The electrocardiographic changes found were prolonged QTc interval, change in ventricular repolarization, and left ventricular hypertrophy. Patients with normal and abnormal electrocardiograms had different metabolic and electrolytic changes
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Alcoholism / Electrocardiography / Heart Diseases Type of study: Etiology study / Observational study / Prevalence study / Risk factors Limits: Adult / Female / Humans Language: English / Portuguese Journal: Arq. bras. cardiol Journal subject: Cardiology Year: 2003 Type: Article Affiliation country: Brazil Institution/Affiliation country: Hospital Espírita de Marília/BR

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Full text: Available Index: LILACS (Americas) Main subject: Alcoholism / Electrocardiography / Heart Diseases Type of study: Etiology study / Observational study / Prevalence study / Risk factors Limits: Adult / Female / Humans Language: English / Portuguese Journal: Arq. bras. cardiol Journal subject: Cardiology Year: 2003 Type: Article Affiliation country: Brazil Institution/Affiliation country: Hospital Espírita de Marília/BR