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Response of the lung after pneumonectomy in alloxan diabetic rats
Seidel, Amélia Cristina; Fagundes, Djalma José; Novo, Neil Ferreira; Juliano, Yara; Meister, Hugo; Bazotte, Roberto Barbosa.
  • Seidel, Amélia Cristina; Universidade Estadual de Maringá. Departamento de Medicina. Maringá. BR
  • Fagundes, Djalma José; Universidade Federal de Säo Paulo. Departamento de Cirurgia. Säo Paulo. BR
  • Novo, Neil Ferreira; Universidade Federal de Säo Paulo. Departamento de Medicina Preventiva. Säo Paulo. BR
  • Juliano, Yara; Universidade Federal de Säo Paulo. Departamento de Medicina Preventiva. Säo Paulo. BR
  • Meister, Hugo; Universidade Estadual de Maringá. Departamento de Medicina. Maringá. BR
  • Bazotte, Roberto Barbosa; Universidade Estadual de Maringá. Departamento de Farmácia e Farmacologia. Maringá. BR
Braz. arch. biol. technol ; 46(2): 211-214, Mar. 2003. tab
Article in English | LILACS | ID: lil-351396
ABSTRACT
In order to determine the response of remaining lung after pneumonectomy during diabetes, female Wistar rats that received an intraperitoneal injection of alloxan (D Group) or saline (C Group) were submitted to lung resection. Six days after alloxan injection (45 mg/kg), diabetes was confirmed. The rats were randomized divided in 3 subgroups non-operated (NO), sham operation (SO) and left pneumonectomy (PE). Thirty days after the surgery all rats were killed and the weight and volume of the lungs were measured. PE-diabetic rats showed smaller lung weight and volume than PE-non-diabetic animals. The results demonstrated that the compensatory lung growth postpneumonectomy were not observed in diabetic rats
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Full text: Available Index: LILACS (Americas) Type of study: Controlled clinical trial Language: English Journal: Braz. arch. biol. technol Journal subject: Biology Year: 2003 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Estadual de Maringá/BR / Universidade Federal de Säo Paulo/BR

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Full text: Available Index: LILACS (Americas) Type of study: Controlled clinical trial Language: English Journal: Braz. arch. biol. technol Journal subject: Biology Year: 2003 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Estadual de Maringá/BR / Universidade Federal de Säo Paulo/BR