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Estomatitis aftosa recurrente. Determinación de marcadores de inmunidad celular / Recurrent aphthous stomatitis. Determination of cell immunity markers
Pérez Borrego, Amparo; Guntiñas Zamora, María Victoria; González Labrada, Carelia.
  • Pérez Borrego, Amparo; Hospital Pediátrico William Soler. CU
  • Guntiñas Zamora, María Victoria; Hospital Pediátrico William Soler. CU
  • González Labrada, Carelia; Hospital Pediátrico William Soler. CU
Rev. cuba. estomatol ; 39(2)mayo-ago. 2002. tab
Article in Spanish | LILACS, CUMED | ID: lil-351645
RESUMEN
La estomatitis aftosa recurrente, aftosis oral o aftas, es la enfermedad más frecuente de todas las lesiones de la mucosa oral. Su etiopatogenia no es completamente conocida, pero se citan factores genéticos, alimentarios, infecciosos, alérgicos, medicamentosos, traumáticos e inmunológicos. Estudiamos 51 pacientes atendidos en el Servicio de Cirugía Maxilofacial del Hospital Pediátrico " William Soler", que padecen de esta enfermedad para valorar el estado de inmunocompetencia celular mediante la determinación del porcentaje de células formadoras de rosetas activas y espontáneas. La edad promedio en nuestro grupo fue de 12 años, ambos sexos se afectaron por igual, y se encontró un predominio franco de los enfermos de raza blanca sobre los de raza negra. El 73 por ciento de los enfermos mostró afectación al menos de un marcador de inmunorrespuesta, 25 pacientes tuvieron ambos marcadores por debajo de lo normal y 12 casos presentaron alteración en uno de los dos. Se concluye que la enfermedad se asocia con defectos de la inmunidad celular, lo cual debe considerarse al indicar tratamiento, teniendo en cuenta que hasta el momento no disponemos de ninguna droga curativa(AU)
ABSTRACT
Recurrent aphthous stomatitis, oral aphthosis or aphthae is the most frequent of all oral mucosal membrane diseases. Its etiology and pathogenesis are not totally known but genetic, food, infectious, allergic, drug, trauma and immunological factors are involved. We studied 51 patients who suffered from this disease and were seen at the Maxillofacial Surgery Department of "William Soler" Pediatric Hospital. Our objective was to assess the cell immunocompetence by determining the percentage of active and spontaneous rosette-forming cells. The average age of the group was 12 years, both sexes were equally affected but white patients greatly prevailed over black patients. At least one immunoresponse marker of 73 percent of the patients was affected; 25 patients had both markers under the normal parameters and 12 cases presented with disturbances in one of the two markers. It was concluded that the disease is linked to cell immunity defects, which should be considered in the treatment, taking into account that no curative drug is so far available(AU)
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Stomatitis, Aphthous / Immunity, Cellular / Immunocompetence Type of study: Diagnostic study Limits: Child / Female / Humans / Male Language: Spanish Journal: Rev. cuba. estomatol Journal subject: Dentistry Year: 2002 Type: Article Affiliation country: Cuba Institution/Affiliation country: Hospital Pediátrico William Soler/CU

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Full text: Available Index: LILACS (Americas) Main subject: Stomatitis, Aphthous / Immunity, Cellular / Immunocompetence Type of study: Diagnostic study Limits: Child / Female / Humans / Male Language: Spanish Journal: Rev. cuba. estomatol Journal subject: Dentistry Year: 2002 Type: Article Affiliation country: Cuba Institution/Affiliation country: Hospital Pediátrico William Soler/CU