Angiogenesis and cancer: recent advances
P. R. health sci. j
;
22(2): 149-151, June 2003.
Article
in English
| LILACS
| ID: lil-356188
RESUMO
Recent studies have shown the possibility to treat cancer with drugs that affect the formation of new blood vessels instead of attacking directly the malignant cell. This relatively new field in the area of oncology on angiogenesis inhibition has expanded the therapeutic option for malignant diseases. We will discuss several antiangiogenesis drugs in clinical development and their mechanism of action. Some of these drugs include angiostatin, metalloproteinase inhibitors, thalidomide, tamoxifen, interferons and others. The use of antiangiogenic agents, both in combination with other treatment modalities in the acute setting as well as long-term maintenance or prevention of cancer, is at present one of the better promises in the war against cancer.
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Index:
LILACS (Americas)
Main subject:
Angiogenesis Inhibitors
/
Neoplasms
/
Neovascularization, Pathologic
Limits:
Humans
Language:
English
Journal:
P. R. health sci. j
Journal subject:
Medicine
Year:
2003
Type:
Article
Affiliation country:
Puerto Rico
Institution/Affiliation country:
San Juan Veterans Affairs Medical Center/PR
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