Clinical trials in isolated systolic hypertension in the elderly
P. R. health sci. j
;
22(2): 145-148, June 2003.
Article
in English
| LILACS
| ID: lil-356189
ABSTRACT
The presence of isolated systolic hypertension in elderly subjects predisposes to the development of coronary artery disease, myocardial infarction, heart failure, cardiovascular events, stroke and cardiovascular mortality. Whether pharmacologic management of isolated systolic hypertension in the elderly is justified or not has not received attention until the recent years. In this era of the practice of evidence based medicine it is important to review the results of clinical trials about the management of isolated systolic hypertension involving thousands of elderly patients. The main trials and their results will be presented. These demonstrate a 17 per cent reduction in total mortality, 25 per cent reduction in cardiovascular mortality, 37 per cent reduction in stroke and a 25 per cent reduction in myocardial infarction for those patients under pharmacologic treatment.
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Index:
LILACS (Americas)
Main subject:
Clinical Trials as Topic
/
Hypertension
Limits:
Aged
/
Humans
Language:
English
Journal:
P. R. health sci. j
Journal subject:
Medicine
Year:
2003
Type:
Article
Affiliation country:
Puerto Rico
Institution/Affiliation country:
University of Puerto Rico/PR
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