Greater genetic variability in Argentine Creole than in Thoroughbred horses based onserum protein polymorphisms
Genet. mol. res. (Online)
;
1(3): 261-265, Sept. 2002. tab
Article
in English
| LILACS
| ID: lil-357428
RESUMO
Genetic polymorphism was analyzed for five blood proteins albumin - Al, esterase - Es, a1B-glycoprotein - Xk, transferrin - Tf and hemoglobin - Hb in 200 Thoroughbred (TB) and 124 Argentine Creole (AC) horses. Of the five systems examined, Tf and Hb were not in Hardy-Weinberg equilibrium in either breed and Es was not in equilibrium in the Creole breed. Genetic variability, estimated as average heterozygosity, was higher in AC (H = 0.585 ± 0.131) than in TB (H = 0.353 ± 0.065). The genetic differentiation between these two populations (FST) was 0.109. Thus, of the total genetic differences between breeds, the proportion of genetic variation attributable to breed differences was about 10%; the remaining 90% was due to individual variation within breeds. The high degree of genetic variability seen in Argentine Creole horses could be a consequence of natural selection. Selection of TB through the centuries has most likely modified the gene pool of the ancestral population, with a consequent reduction in variability at certain loci. Probably, different mechanisms exist for maintaining polymorphism at these loci in TB and in AC horses. Heterozygosity may have played a fundamental role in adaptation.
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Index:
LILACS (Americas)
Main subject:
Polymorphism, Genetic
/
Genetic Variation
/
Blood Proteins
/
Horses
Limits:
Animals
Country/Region as subject:
South America
/
Argentina
Language:
English
Journal:
Genet. mol. res. (Online)
Journal subject:
Molecular Biology
/
Genetics
Year:
2002
Type:
Article
Affiliation country:
Argentina
Institution/Affiliation country:
Universidad Nacional de la Plata/AR
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