Correlation between symptoms of the irritable bowel syndrome and the response to the food extract skin prick test
Braz. j. med. biol. res
;
37(5): 659-662, May 2004. tab
Article
in English
| LILACS
| ID: lil-357546
ABSTRACT
The relationship between the irritable bowel syndrome (IBS) and food intolerance is not clear. We studied the cutaneous response to food antigens in 43 volunteers who were students and employees of the Faculty of Medicine of Universidade Federal Fluminense. Subjects were divided into 3 groups after evaluation for Roma II criteria for functional disease of the gastrointestinal tract group I, 14 volunteers with IBS; group II, 15 volunteers with functional dyspepsia; group III, 14 volunteers without habitual gastrointestinal symptoms. The subjects were submitted to the skin prick test with 9 food antigen extracts, for a total of 387 skin tests (9 per volunteer). Of the 126 tests applied to group I, 24 (19.4 percent) were positive (a 3-mm wider papule than the negative control) and of the 135 tests applied to group II, 3 (2.3 percent) were positive. Of the 126 tests applied to group III, 6 (4 percent) were positive. The number of positive responses obtained in group I (IBS) differed significantly from the other 2 groups (P < 0.01). None of the volunteers with IBS reported intolerance to any isolated food. The higher reactivity to food antigens in group I compared to groups II and III suggests that intestinal permeability may be increased in patients with IBS.
Full text:
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Index:
LILACS (Americas)
Main subject:
Skin Tests
/
Irritable Bowel Syndrome
/
Food Hypersensitivity
/
Antigens
Type of study:
Diagnostic study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
2004
Type:
Article
/
Congress and conference
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal Fluminense/BR
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