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Densidad mineral ósea en escolares nacidos prematuros / Bone mineral density in school age children born preterm
Milinarsky T, Aída; Fischer G, Sylvia; Giadrosich R, Vinka; Hernández C, María Isabel; Torres C, María Teresa.
  • Milinarsky T, Aída; Universidad de Valparaíso. Facultad de Medicina. Departamento de Pediatría. CL
  • Fischer G, Sylvia; Universidad de Valparaíso. Facultad de Medicina. Departamento de Pediatría. CL
  • Giadrosich R, Vinka; Universidad de Valparaíso. Facultad de Medicina. Departamento de Pediatría. CL
  • Hernández C, María Isabel; Universidad de Valparaíso. Facultad de Medicina. Departamento de Pediatría. CL
  • Torres C, María Teresa; Universidad de Valparaíso. Facultad de Medicina. Departamento de Pediatría. CL
Rev. méd. Chile ; 131(11): 1289-1294, nov. 2003. ilus, tab
Article in Spanish | LILACS | ID: lil-358948
RESUMO
The age at which children born preterm normalize their bone mineral density, is not well known.

Aim:

To study if children born preterm have normalized their bone mineral density at age 5 to 7 years. Patients and

methods:

Twenty six infants born preterm (14 male), were studied at age 5 to 7 years. Birth weight, present weight and height, bone age, calcium and phosphate intake at the first year of life and at the current age were assessed. Bone mineral density was measured by single photon X ray absorptiometry in the dominant forearm. A blood sample was obtained to measure insulin growth factor 1 (IGF-1). As a control group, 105 healthy age-paired infants born at term, were studied.

Results:

Bone mineral density was significantly lower in infants born preterm than in their term counterparts (0.273±0.01 g/cm2 and 0.302±0.01 g/cm2 respectively, p <0.001). There was a positive correlation between bone mineral density and IGF-1 (r=0.49, p=0.01). No correlation with the other measured parameters was observed.

Conclusions:

Infants that were born preterm have a lower bone mineral density at 5 to 7 years of age than their term controls. Bone mineral density correlates with IGF-1 (Rev Méd Chile 2003; 131 1289-94).
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Birth Weight / Infant, Premature / Bone Density Type of study: Observational study Limits: Child / Child, preschool / Female / Humans / Male / Infant, Newborn Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2003 Type: Article Affiliation country: Chile Institution/Affiliation country: Universidad de Valparaíso/CL

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Full text: Available Index: LILACS (Americas) Main subject: Birth Weight / Infant, Premature / Bone Density Type of study: Observational study Limits: Child / Child, preschool / Female / Humans / Male / Infant, Newborn Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2003 Type: Article Affiliation country: Chile Institution/Affiliation country: Universidad de Valparaíso/CL