Evaluation of cholinesterase level in an endemic population exposed to malathion suspension formulation as a vector control measure
Mem. Inst. Oswaldo Cruz
;
99(2): 219-221, Mar. 2004. tab
Article
in English
| LILACS
| ID: lil-360979
RESUMO
The manuscript describes a study on the blood cholinesterase (ChE) level in an exposed population at different interval of time after spraying with malathion suspension (SRES) use for kala-azar vector control in an endemic area of Bihar, India. The toxicity of a 5 percent malathion formulation in the form of a slow release emulsified suspension (SRES) was assessed by measuring serum ChE levels in spraymen and in the exposed population.The study showed a significant decrease in ChE levels in the spraymen (p < 0.01) after one week of spraying and in exposed population one week and one month after of spraying (p < 0.01), but was still within the normal range of ChE concentration, one year after spraying, the ChE concentration in the exposed population was the same as prior to spraying (p > 0.01). On no occasion was the decrease in ChE level alarming. A parallel examination of the clinical status also showed the absence of any over toxicity or any behavioural changes in the exposed population. Hence, it may be concluded that 5 percent malathion slow release formulation, SRES, is a safe insecticide for use as a vector control measure in endemic areas of kala-azar in Bihar, India so long as good personal protection for spraymen is provided to minimize absorption and it can substitute the presently used traditional DDT spray.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Phlebotomus
/
Cholinesterases
/
Environmental Exposure
/
Insecticides, Organophosphate
/
Insect Vectors
/
Malathion
Limits:
Animals
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2004
Type:
Article
/
Project document
Affiliation country:
India
Institution/Affiliation country:
Rajendra Memorial Research Institute of Medical Sciences/IN
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