Single institutional retrospective analysis: treatment of choroidal melanomas with cobalt-60 brachytherapy
Arq. bras. oftalmol
;
67(3): 451-454, maio-jun. 2004. tab, graf
Article
in English
| LILACS
| ID: lil-361697
RESUMO
Purpose:
To evaluate the autcome pf patients with choroidal melanoma treated with conservative therapy with brachytherapy (episcleral Co-60 plaque therapy) at the "Hospital do Cancer"São Paulo, Brazil.Methods:
We evaluated 102 patients consecutively treated from January, 1999 to June, 1999. Median age, maximum tumor base diameter and apex size were 55.5 years, 9.75 and 5mm, respectively. Dose s at the base of the tumor, including 1 mm of sclera, ranged from 157 to 487 Gy (median 284.5 Gy) and to the apex from 37 to 220 Gy (median 106 Gy).Results:
The crude eye preservation rate with conservative therapy alone was 78.5 percent. Five-year overall actuarial survival rate was 92.2 percent and eye conservation rate was 78 percent. Side effects were mostly and uncomplicated retinopathy in 39/102 patients (38.2 percent); macular degeneration or scarring led to poor central vision in 31/102 patients (30.3) of cases.Conclusion:
Our experience with cobalt-60 plaque brachytherapy achieved a satisfatory rate of local tumor control, despite the oversized base diameters of theated tumors.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Brachytherapy
/
Choroid Neoplasms
/
Cobalt Radioisotopes
/
Melanoma
Type of study:
Observational study
Limits:
Adolescent
/
Adult
/
Aged80
/
Female
/
Humans
/
Male
Language:
English
Journal:
Arq. bras. oftalmol
Journal subject:
Ophthalmology
Year:
2004
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Centro de Tratamento Pesquisa Hospital do Câncer - AC Camargo/BR
/
Escola Paulista de Medicina/BR
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