Klebsiella pneumoniae with multiple antimicrobial resistance
Braz. j. infect. dis
;
8(1): 109-111, Feb. 2004. ilus
Article
in English
| LILACS
| ID: lil-362373
ABSTRACT
A Klebsiella pneumoniae strain was isolated from the urine of a patient at one of the centers participating in the 2001 edition of the MYSTIC program in Brazil. The initial phenotypic findings of the isolated K. pneumoniae presented an unusual MIC of 8 ìg/mL to meropenem, 2 ìg/mL to imipenem, elevated MICs to broad spectrum cephalosporins (ceftazidime/cefotaxime/cefepime MIC > 256 ìg/mL), aminoglycosides (gentamycin > 256 ìg/mL and tobramycin = 48 ìg/mL), piperacillin/tazobactam (MIC > 256 ìg/mL) and susceptibility to ciprofloxacin (MIC = 0.25 ìg/mL). The strain also tested positive for ESBL production with double-disk and E-test methodologies. More detailed investigation revealed that the strain produced a SHV-4 type enzyme and also lacked a 36 kDa outer membrane porin.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Klebsiella Infections
/
Drug Resistance, Multiple
/
Klebsiella pneumoniae
/
Anti-Bacterial Agents
Limits:
Humans
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2004
Type:
Article
Affiliation country:
Brazil
/
United kingdom
Institution/Affiliation country:
Antrazeneca Macclesfield/GB
/
Fleury Medical Diagnostic Center/BR
/
Hospital de Base of Brasília/BR
Similar
MEDLINE
...
LILACS
LIS