Evaluación ultrasonográfica de la función endotelial en niños y adultos chilenos / Ultrasound assessment of endothelial function in Chilean children and adults
Rev. méd. Chile
;
132(4): 437-444, abr. 2004. ilus, tab, graf
Article
in Spanish
| LILACS
| ID: lil-362908
ABSTRACT
Background:
Endothelial dysfunction is an important pathogenetic mechanism in the development of atherosclerosis.Aim:
To evaluate endothelial function in Chilean children and adult subjects and to provide normal values of flow mediated dilatation (FMD) in the Chilean population. Subjects andMethods:
Flow mediated dilation of the brachial artery was measured by high resolution ultrasonography in healthy children (n=32) and adults (n=69) of both gender, in a group of 8 healthy women during 4 periods of pregnancy and late postpartum, and in 22 men and women with a history of stroke or coronary heart disease.Results:
FMD in boys and girls was 9.9±3.6 and 10.0±4.2% respectively (NS). The figures for young women and young men were 11.3±3.8 and 8.6±3.9, respectively (p=0.02); for postmenopausal women and older men, 5.5±6.6 and 7.6±6.7 respectively (NS). During normal pregnancy and postpartum there were no significant changes in FMD. Patients with cardiovascular disease had a FMD of 0.3±5.2%, (p <0.001, with other groups).Conclusions:
The present study provides values of FMD in healthy Chilean subjects of different ages, and in patients with coronary heart disease.
Full text:
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Index:
LILACS (Americas)
Main subject:
Ultrasonography
/
Endothelium
Type of study:
Diagnostic study
/
Etiology study
/
Evaluation studies
/
Risk factors
Limits:
Adult
/
Child
/
Female
/
Humans
/
Pregnancy
Country/Region as subject:
South America
/
Chile
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2004
Type:
Article
/
Project document
Affiliation country:
Chile
Institution/Affiliation country:
Pontificia Universidad Católica de Chile/CL
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