Relationship between functional and X-ray alterations in patients with cystic fibrosis
J. pneumol
;
29(4): 196-201, jul.-ago. 2003. tab, graf
Article
in English
| LILACS
| ID: lil-366304
RESUMO
BACKGROUND: Cystic fibrosis (CF) is a disease marked by airway inflammation and airflow obstruction, resulting in air trapping in the lungs. OBJECTIVE: To assess the associations between airflow limitation, pulmonary volume and X-ray findings in patients with cystic fibrosis. METHOD: A cross-sectional retrospective study. Review of spirometric, plethysmographic, and chest X-ray findings of outpatients (age 16 years). The airflow findings were classified as within normal limits or as airflow obstruction: mild, moderate or severe obstructive alteration. RESULTS: A total of 23 patients (15 male and eight female; mean age, 21 ± 5.9 years) were studied. Six of them were within normal limits, four had a mild, five had a moderate, and eight had a severe obstructive alteration. There was an association between airflow limitation and the increase of residual volume (p = 0.006) and also with the Brasfield score (p = 0.001), but not with the total lung capacity (p = 0.33). There was a correlation between residual volume and Brasfield score (r = 0,73, p = 0,002), but not with the total pulmonary capacity. Moreover, according to X-ray criteria, the air trapping was correlated only with the residual volume (p = 0.006). CONCLUSION: In patients with cystic fibrosis (age 16 years), the progressive airflow limitation is accompanied by an increase in residual volume, while the total pulmonary capacity remains normal or tends to decrease. The X-ray score was associated with airflow limitation and residual volume, but not with total lung capacity.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Tidal Volume
/
Cystic Fibrosis
/
Lung Volume Measurements
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
J. pneumol
Journal subject:
Pulmonary Disease (Specialty)
Year:
2003
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Hospital das Clínicas de Porto Alegre/BR
/
Universidade Federal do Rio Grande do Sul/BR
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