Persistence of viable bacilli in highly bacilliferous multibacillary leprosy patients after the twelve doses of multidrug therapy WHO/MDT
Hansen. int
;
28(1): 49-52, jan.-jun. 2003. tab
Article
in English
| LILACS
| ID: lil-383916
RESUMO
The present study evaluate efficacy of twelve doses of multidrug therapy, as suggested by World Health Organization, in ten lepromatous leprosy patients with bacilloscopic index equal or higher than 4. The patients have taken the doses in twelve month-doses regularly. At the end od treatment a specimen was collected by punch biopsy and inoculated into mouse hind footpad acoording to Shepard's technique. Persistence of viable bacilli was demonstrated in three patients. In spite of the small number of patients, same results have been found by other authors, showing that in highly bacilliferous leprosy patients, at the beginning of treatment more doses may be required to prevent relapses.
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Index:
LILACS (Americas)
Main subject:
Leprosy
/
Microbiology
/
Mycobacterium leprae
Language:
English
Journal:
Hansen. int
Journal subject:
Hansen¡ase
/
Tropical Medicine
Year:
2003
Type:
Article
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