Nefritis intersticial aguda y lamotrigina / Acute interstitial nephritis associated to lamotrigine use: report of one case
Rev. méd. Chile
;
132(6): 742-746, jun. 2004. ilus, tab
Article
in Spanish
| LILACS
| ID: lil-384223
ABSTRACT
Acute interstitial nephritis is a mononuclear and sterile inflammation of the renal interstice caused by drugs, infections or immune phenomena. The clinical presentation is characterized by the triad of rash, fever and eosinophilia. We report a 32 years old man, in treatment with lamotrigine for depression, admitted to the hospital due to fever, abdominal pain, jaundice, cutaneus rash and malaise. Due to an oliguric renal failure of acute onset, a renal biopsy was done. The pathological study showed a granulomatous acute interstitial nephritis. He was started on hemodialysis and treated with cessation of the drug and corticosteroids, with complete recovery of the renal function (Rev Méd Chile 2004; 132 742-6).
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Antidepressive Agents
/
Nephritis, Interstitial
Type of study:
Risk factors
Limits:
Adult
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2004
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Clínica Dávila/CL
/
Pontificia Universidad Católica de Chile/CL
/
Universidad de los Andes/CL
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